[Comment] Ten years of advances in disorders of gut–brain interaction

Abstract

Disorders of gut–brain interaction (DGBI), including irritable bowel syndrome (IBS) and functional dyspepsia, are a group of conditions previously termed functional gastrointestinal disorders, in which individuals report chronic or recurrent gastrointestinal symptoms in the absence of a structural explanation. They are mostly diagnosed through a combination of limited investigations and symptom-based criteria. DGBI account for a substantial proportion of the outpatient workload of gastroenterologists, and are underserved in terms of clinical engagement and research funding.